There is a regular bus service from Mien Tay station in Ho Chi Minh City to Mytho beginning early morning. It takes about 2 hours to cover the 70km. There is also a hydrofoil service that runs to/from Ho Chi Minh City three times per week.
Boat trips are the highlight of a visit to Mytho. Usually, destinations include a coconut workshop, a honey bee farm and orchard gardens. If time allowed, should not miss Vinh Trang Pagoda, a beautiful and well maintained sanctuary and Dong Tam snake farm, a center for breeding snakes producing venom for exportation.